Amy Mathers, M.D., D(ABMM)
University of Virginia, Charlottesville
Amy Mathers, M.D., B(ABMM), is a professor of medicine and pathology and the Bayer Corporation/Gerald L. Mandell Professor of Internal Medicine at the University of Virginia School of Medicine. She is an infectious diseases physician with a 15-year history of serving as the medical director of antimicrobial stewardship. She has been the associate director of clinical microbiology for over a decade and has served as the Director of the Clinical Microbial Sequencing Laboratory (AMR Services) for the University of Virginia Health System for the past 5 years. Mathers has established herself as a leader in bridging clinical care, laboratory science and public health with a focus on antimicrobial resistance in bacterial species.
In the clinical laboratory, Mathers has led the implementation of susceptibility testing approaches, paired with clinical action to optimize appropriate antimicrobial prescribing. She has been influential in building academic/public health partnerships for the adaptation of genomic tools to track organism transmission. She has demonstrated how microbiology laboratories can drive infection prevention to reduce the spread of antimicrobial resistance. She has pioneered innovative approaches to understanding resistance gene movement, integrating genomics, epidemiology and mathematical modeling to address critical knowledge gaps.
Through her leadership on national committees, including the Clinical and Laboratory Standards Institute (CLSI) Antimicrobial Susceptibility Testing Subcommittee, where she now serves as chair, Mathers has helped shape practice standards that impact laboratories worldwide.
Her career embodies the integration of clinical service, research innovation and national leadership that continues to advance the field of clinical microbiology.